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Vitamin D itself has still a much lower affinity. Vitamin D 2 metabolites bind slightly less well to human DBP than vitamin D 3 metabolites, whereas chick DBP has a much lower affinity for vitamin D 2 metabolites for otherwise unexplained structural reasons, winstrol depot stanozolol 50mg side effects. It is also well known that vitamin D 2 has poor antirachitic properties in birds, and it is attractive to link that to differences in DBP affinities, although direct proof is missing. The VDR has a much higher (about 100-fold) affinity for 1,25(OH) 2 D than for 25OHD.
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