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McNeil's study showed that while athletes did sometimes have a higher incidence of kidney stones or an irregular sperm count, this risk was not as great as his prediction (which was based on a prevalence of 5% in athletes) suggested. In 1988, researchers published another study which determined that the incidence of a particular disease in professional, elite, and high-performance athletes correlates with their testosterone ratio, . This was not unexpected, as the concentration of T and other androgens in the blood of these athletes is approximately 1000 times that of untrained controls. While androgens do have some medical benefits, they do not possess the same positive effects as other drugs of abuse.

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